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Benefits of Omega 3
Omega 3 and Pregnancy
According to Crawford (1995), the first pregnancy-related need for PUFAs (both omega-6 and omega-3) occurs during the three months prior to conception. This critical period for cell commitment and division requires ARA and DHA to facilitate growth and development. It has been suggested that supplementation with fish oil, or increased fish intake, during pregnancy prevents the pregnancy-induced hypertension, prolongs gestation, increases birth weight and reduces the incidence of premature birth (Gerrard et al, 1991, Olsen et al, 1992). Recent data support the view that the intake of DHA during pregnancy should be in the amount of at least 0.1-0.4 g/day (Crawford, 1995).
Fetal stage
DHA is important for optimal nervous system development. During the last trimester of pregnancy, when the fetal demand for neural and vascular growth are greatest, there is an elevated accretion of DHA in the liver and brain of the fetus. A maternal diet high in DHA will greatly enrich the DHA concentration in the blood of the newborn infant. Even levels as low as 0.7g EPA+DHA/day during the period from 25th to 35th week of pregnancy seem to be beneficial (Connor et al, 1995). DHA levels in maternal plasma are lower in multigravidae compared to primigravidae and the smaller the baby, the lower DHA-level (Al et al, 1995). Consequently, it is therefore especially important for multigravidae to increase the intake of DHA.
Pre-eclampsia
During pregnancy, blood lipids, triglycerides and cholesterol may rise several folds. There may also be an increase in blood pressure. The risk of developing pre-eclampsia and subsequent premature birth is increased if these, otherwise normal changes are increased above certain levels. Severe forms of pregnancy-induced hypertension have been reported to be beneficially modulated by omega-3 fatty acids (Secher et al, 1991). In light of their very strong hypotriglyceridemic and hypotensive effects, omega-3 fatty acids along with other nutritional factors, may be significant for the prevention of pre-eclampsia. The maternal blood pressure responses depend on the ARA/EPA ratio in the vessel wall. Multicenter studies are currently in progress and the first results are expected to be available primo 1997. In the meantime, it would generally seem prudent to recommend an increased intake of omega-3 fatty acids during pregnancy. EPA will benefit the mother's heart and circulation, and DHA will definitely be good for the development of fetal brain and nervous system.
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